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- 白色或几乎白色结晶性粉末。溶于水。
熔点:215℃ (分解)
质量标准
项目 USP级
(USP grade)
含量Assay 91.0 - 100.5 % (HPLC)
比旋光度α20/D;: +258°- +287°(0.25 %, 邻苯二甲酸氢钾溶液,4 g/L )
溶液外观Appearance of solution: 符合
细菌内毒素Bacterial endotoxins: ≤0.15 I.U./mg
重金属Heavy metals (as Pb): ≤0.002 %
鉴别试验Identification: 符合
pH (10 %; H2O): 8.0 - 10.0
相关物质Related substances: 符合
2-乙级己酸2-Ethylhexanoic acid: ≤0.8 %
二氯甲烷Dichloromethane ≤0.2 % (m/m) (GC)
N,N-二甲基苯胺N,N-Dimethylaniline:≤0.002 %
水分Water ≤2 %(K.F.)
效价Potency (anhydrous) 845-988 mcg/mg
品级Grade 细胞培养专用
(cell culture tested)
外观Appearance白色至带点黄色的粉末
红外光谱鉴别Infrared spectrometry Conforms
水分Water ≤2 %(K.F.)
含量Assay 91.0 - 100.5 % (HPLC)
效价POTENCY ≥ 845 UG AMPICILLIN/MG
细胞培养测试Cell culture test PASS
贮存:2-8℃保存。
用途;半合成的青霉素,抗革兰氏阳性及阴性菌。
属β-内酰胺酶抗生素,氨基基团链连接到青霉素结构上。属青霉素衍生物,依靠在细菌细胞膜的内层面使转肽酶(transpeptidases)失活抑制细菌细胞壁的合成。
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