G418硫酸盐
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别名：
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G-418硫酸盐;抗菌素G-418;抗生素G-418
产品介绍
MSDS与安全信息
质检证书(CoA)
相关产品
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介绍： G418是一种氨基糖苷类抗生素 ,这种氨基糖类抗生素的结构和新霉素、庆大霉素、卡那霉素相似，在分子遗传试验中,是稳定转染最常用的抗性筛选试剂。它通过抑制转座子Tn601，Tn5的基因,干扰核糖体功能而阻断蛋白质合成,对原核和真核等细胞产生毒素 ,包括细菌、酵母、植物和哺乳动物细胞 ,也包括原生动物和蠕虫。当neo基因被整合进真核细胞DNA后 ,则能启动neo基因编码的序列转录为mRNA ,从而获得抗性产物氨基糖苷磷酸转移酶的高效表达 ,使细胞获得抗性而能在含有 G418的选择性培养基中生长靠干扰核糖体功能阻断多肽合成。不是常用的标准抗生素，常用于选择新霉素抗药基因转染的原核和真核细胞。在基因转移、基因敲除、抗性筛选以及转基因动物等方面得以广泛应用。
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Strict Standards: Only variables should be passed by reference in /home/hualanchemlhfu9a8l2a2n4cshvetm/wwwroot/includes/cls_template.php on line 422
Strict Standards: Only variables should be passed by reference in /home/hualanchemlhfu9a8l2a2n4cshvetm/wwwroot/includes/cls_template.php on line 422
Strict Standards: Only variables should be passed by reference in /home/hualanchemlhfu9a8l2a2n4cshvetm/wwwroot/includes/cls_template.php on line 422
Strict Standards: Only variables should be passed by reference in /home/hualanchemlhfu9a8l2a2n4cshvetm/wwwroot/includes/cls_template.php on line 422
Strict Standards: Only variables should be passed by reference in /home/hualanchemlhfu9a8l2a2n4cshvetm/wwwroot/includes/cls_template.php on line 422
Strict Standards: Only variables should be passed by reference in /home/hualanchemlhfu9a8l2a2n4cshvetm/wwwroot/includes/cls_template.php on line 422
Strict Standards: Only variables should be passed by reference in /home/hualanchemlhfu9a8l2a2n4cshvetm/wwwroot/includes/cls_template.php on line 422
