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英文名称:Polymyxin B sulfate
其他名称:多胜菌素乙;硫酸多粘菌素B;多粘菌素B硫酸酯;硫酸阿罗多粘
CAS号:1405-20-5
C55H96N16O13·2H2SO4= 1385.61
级别:USP Grade
效价:≥6500Iu/mg
PH:5.0~7.0
比旋光度:-78~-90º
干燥失重:≤6.0%
性状:白色至类白色或微黄色粉末;无臭或几乎无臭。有引湿性。在水中易溶,在乙醇中微溶,在丙酮、氯仿或乙醚中几乎不溶
用途:生化研究。多粘菌素B为抗革兰阴性杆菌多肽类抗生素,
可以改变膜结构使小分子物质泄漏而抑制革兰氏阴性菌的生长。对大肠杆菌具有杀菌作用。结合到细菌脂多糖类的脂质A部分。在外皮细胞膜诱发小孔。
作用模式: 结合并干涉细胞质膜的渗透性。抗菌谱: 革兰式阴性细菌。
保存:2~8℃
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