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- 壳聚糖是一种线性氨基多糖,由大约20%β1,4 -连接的N -乙酰- D -氨基葡萄糖(葡萄糖胺),和大约80%的β1,4 -连接的D -氨基葡萄糖(GlcN)组成,由甲壳素在热碱液中部分脱乙酰准备而成。不溶于水,羧化壳聚糖经羧化处理,溶于水
质量标准
高密度壳聚糖(M.W. 100,000-300,000)
外观Appearance类白色至黄褐色粉末或颗粒
脱乙酰度Deacetylation value ≥95%
水份Water <8 % (K.F.)
灰份Ash <1 %
粘度viscosity ≤100mpa.s
砷Arsenic(以As计) ≤0.5ppm
重金属Heavy metals(as Pb) ≤10ppm
堆积密度bulk density≥0.6 g/ml
细菌菌落总数bacterial count ≤1000cfu/g
大肠杆菌E.coli≤30 cfu/g
沙门氏菌Salmonella不得检出
羧化壳聚糖:(水溶性壳聚糖)
外观Appearance透明至半透明白色或微黄色不定形固体
羧化度Carboxylation ≥60%
粘度viscosity(1%水溶液) 10-80mpa.s
pH (1%的水溶液) 6.0-8.0
干燥失重Loss on drying≤15.0%
不溶物Insoluble matter< 0.5%
重金属Heavy metals< 5.0ppm
低粘度(<200 mPa.s):
不溶物insoluble matter ≤1%
灼烧残渣ign. residue ≤2% (as SO4)
干燥损失loss on drying ≤10%
粘度viscosity<200 mPa.s, 1 % in acetic acid(20 °C)
中粘度(200-400 mPa.s):
不溶物insoluble matter ≤1%
灼烧残渣ign. residue ≤2% (as SO4)
干燥损失loss on drying ≤10%
粘度viscosity200-400 mPa.s, 1 % in acetic acid(20 °C)
高粘度(>400 mPa.s):
不溶物insoluble matter≤1%
灼烧残渣ign. residue≤2% (as SO4)
干燥损失loss on drying≤12%
粘度viscosity >400 mPa.s, 1 % in acetic acid(20 °C)
贮存
用途:壳聚糖是一种具生物相容性、抗细菌和能被生物降解的聚电解质,具有广泛的生物医药和工业用途。它的化学性质和低毒性可作为药物的组成部分、用于基因转移系统、用作生物降解膜及作为组织工程中的骨架。
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