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- 介绍: DaunorubiCln HCl抑制DNA和RNA合成,抑制DNA合成时,Ki为0·02 μM。强效抗癌剂,已证明是 DNA 和 RNA 合成的强抑制剂。自发荧光的蒽环类抗生素,抗癌药。Pgp、MRP-1 和 BCRP 的底物。已利用荧光特性来测量药物外排泵活性,以及解?决许多重要问题,如多种多药耐药蛋白的胞内定位和亚细?胞器(高尔基体和溶酶体)在药物螯合中的作用及其在耐?药表型中的含义。根据 pH 分配型机理将柔红霉素螯合进溶酶体。DNA 和 RNA 合成的强抑制剂。
- 储存条件: -20℃
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